Case of the Week | Pathology

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Details: Published: November 11th, 2026

Case History:

A 29-year-old female with a clinical history of polycystic ovarian syndrome (PCOS), abnormal uterine bleeding, and hirsutism presents with a 4.5 cm partially cystic left ovarian mass. Slides were received in consultation. Immunohistochemical staining revealed the tumor cells were positive for SF1, calretinin, and MART-1 (patchy), and negative for S100 and HMB45.

Details: Published: October 27th, 2026

Case History:

A 69-year-old man presents with a painless testicular lump. Scrotal ultrasound shows a 3 cm mass above the testicle.

Details: Published: October 9th, 2026

Case History:

A young adult patient with a history of HIV presents with epigastric pain. On upper GI endoscopic exam, there are multiple erythematous mucosal nodules seen throughout the duodenum. A biopsy of a nodule was taken. H&E, ERG, and HHV-8 stains are shown.

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Details: Published: May 5th, 2026

Case History:

Lung nodule FNA from a female with bilateral pulmonary nodules and a history of primary breast neoplasm.

Details: Published: April 21st, 2026

Case History:

A 55 year-old presents with nodular mass in the temporomandibular joint with erosion of the glenoid fossa. Histologic sections from this lesion are shown below.

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