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Center for Clinical and Translational Science

Informatics

sharpening your scienceCCTS Informatics provides the resources and expertise (both bioinformatics and clinical informatics) to support biomedical collaboration and consultation across the translational research spectrum. We offer help with study design; access to summary, limited (de-identified), and fully identified data sets; innovative tools to support clinical, translational, and outcomes research; and data analytic services. Our vision is to build a vibrant community of collaborating informaticians not only across the CCTS Hub with its academic medical system, but also across the regional CCTS Partner Network and national CTSA Consortium.

CCTS Bioinformatics

CCTS Bioinformatics provides data and analytic support for the following:

  • Next Generation Sequence Analysis
  • Microarray analysis
  • Microbiome
  • Single cell and other 'omics analyses
Contact CCTS@uab.edu with any questions.

CCTS Clinical Research Informatics

CCTS Clinical Research Informatics provides investigators with access to UAB electronic health record (EHR) data via either (1) our self-service tools (i2b2) or (2) an Electronic Data Warehouse (EDW) analyst. 

  • UAB EHR Data Resources
    • DataLENS
    • i2b2
  • Outside Data Networks
    • ENACT Network (formerly ACT Network)
    • All of Us Workbench
    • National Clinical Cohort Collaboration (N3C)
    • PCORnet
      • OneFlorida+
      • REACHnet
    • TriNetX
    • Alabama Genomic Health Initiative (AGHI)
  • Tools and Services
    • Data2Discovery Gateway Special Interest Group
    • PowerTalk Series
    • Data storage, management, and sharing plans
CCTS Informatics offers three levels of clinical data:
Level 1 –
Summary Data
  • Aggregated patient counts; no Protected Health Information (PHI)
  • IRB approval for use is NOT required (per IRB protocol E160105006)*
  • Appropriate for cohort/enrollment feasibility, correlational studies
  • Accessible via self-service tools (i2b2 and ACT Network) 
 Level 2 – Limited (De-identified)
Detailed Data

  • Includes limited identifiers (dates and geographic locations larger than street addresses)
  • IRB approval for use is NOT required (per IRB protocol E160105006)*
  • Appropriate for recruitment or retrospective analyses
  • Accessible via i2b2 self-service tool 
 Level 3 – Fully Identified Detailed Data
(only accessible through an Analyst)
  • Patient-level data, with PHI
  • IRB approval required
  • Appropriate for recruitment or prospective
 

*NOTE: It is possible that funding agencies or journal publishers may require documentation of IRB approval regardless of UAB IRB policy. If so, contact IRB directly to request documentation of approval for Level 1 and Level 2 data sets.