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Frequently Asked Questions

  • IRB

    • What criteria were used to determine whether a protocol was considered "active" and eligible for automatic transfer from IRAP into MURE?

      The primary criterion for automatic transfer was current IRB approval. Any study that held a valid, unexpired IRB approval at the time of the transition was considered active and was migrated into myUABResearch. This approach ensured that ongoing research could continue without interruption and that study teams would not need to resubmit studies that were already approved and in progress.

      Note that exempt studies more than one year old were not migrated into MURE. These protocols meet the criteria that means they are not subject to (exempt from) the human subjects regulations in the way that expedited and convened studies are. This is why there is not a continuing review requirement. Any change to one of the exempt projects is an entirely new determination, not a continuation of approval b/c it was never an approval. Because exempt determinations do not carry an expiration date or require continuing review, they were managed differently during the transition. These studies remain valid under their existing determinations and documentation in IRAP, and study teams only need to enter them into myUABResearch if a modification requiring a protocol is needed, as described below.

    • Is there a mechanism for transferring archived or inactive protocols that remain important for publications, audits, or future amendments?

      Archived or inactive protocols cannot be transferred into myUABResearch. Their documentation remains accessible in the IRAP archive, including prior submissions, approval correspondence, and other records needed for publications, audits, or study-history questions.

      Study teams must maintain complete regulatory documentation and study records in hard-copy or electronic regulatory binders, regardless of transfer status. The IRAP archive supports retrieval but does not replace this responsibility. Studies closed before the transition remain subject to applicable record-retention policies.

      For publications or audits, teams may reference IRAP documentation and their regulatory binders. Archived records do not establish that a protocol can be amended or that research may resume under its previous status.

      Before changing an archived or inactive study, consult HRPP about the appropriate submission pathway and whether a new submission is required. Access to historical records does not replace required review and approval for future research.

    • My exempt protocol is not in myUABResearch, how do I submit changes?

      Only exempt protocols more than one year old may require a bridge submission into myUABResearch (MURE). All other studies with current IRB approval were migrated automatically. These exempt studies remain valid under their existing determinations, so a MURE submission is not required simply because the system changed. The study team only needs to enter the study into MURE and submit a modification when a change is needed.

      Teams with exempt studies older than one year do not need to start from scratch. The Office of Research developed an AI tool that maps existing IRAP e-portfolio information into the new MURE protocol template, reducing manual re-entry. Because the e-portfolio may not contain every element the new template requires, teams must review the draft and complete or update those sections before submitting. Problems with the tool should be reported through an ASK IT ticket.

    • I am a proxy for a PI, how do I get added to their existing studies?

      To request PI proxy access, log a ticket requesting this access. This functionality...

      • adds PI proxies to existing IRB submissions overnight, and
      • automatically adds PI proxies to new IRB submissions.
    • Which submission documents will be migrated into myUABResearch?
      Attachments from the study record and the ePortfolio will not be migrated into myUABResearch.
    • When do I need to upload a protocol document?
      Submission TypeProtocol Document Required
      Modification of Study Team Members InformationNo
      Continuing ReviewNo
      Study ClosureNo
      Adding a pSite to a sIRB StudyNo
      New StudyYes
      Modification of Other Parts of the StudyYes
    • What if I have an issue that affects the safety of research participants?
      Investigators must conduct research activities in accordance with the terms of the IRB approval except when necessary to eliminate apparent immediate hazards to the subject (45 CFR 46.108(3)(iii). If a change must be made in real time to avoid harm to a participant, that is allowable. However, an investigator may not make planned changes to the approved protocol without IRB approval. Protocol amendments must be submitted and approved prior to the submission freeze period if changes will be needed. Please plan accordingly.
    • Where can I get additional information about the myUABResearch IRB module?
      Additional information about the myUABResearch IRB module can be found at https://www.uab.edu/research/home/myuabresearch/irb. This website includes information about the system implementation timeline, as well as training offerings so that you are ready to fully utilize the new system on day one.
    • How will the IRB application in myUABResearch differ from IRAP?
      The IRB module in myUABResearch uses a simplified application compared to IRAP. Much of the detailed, study-specific information previously entered directly into the IRAP ePortfolio will instead be documented in the research protocol document and other uploaded documents.
    • Will the IRAP ePortfolio be migrated into myUABResearch?
      No. The IRAP ePortfolio itself will not be imported into the myUABResearch IRB module. Only basic study information for approved study records will appear in myUABResearch. Investigators should not rely on the IRAP ePortfolio as the primary source of study documentation after conversion.
    • Are there any tools to help me create my research protocol for myUABResearch?
      Yes. UAB has developed an AI-powered protocol tool based on the HRPP Toolkit protocol templates. This tool helps investigators draft a research protocol in the same format and structure as the Toolkit templates. The “IRB Draft Tool” can be accessed here under the myResearch tab at my.uab.edu

      Because the myUABResearch IRB module relies more heavily on the protocol document (rather than structured ePortfolio fields), investigators are encouraged to use this tool to develop a complete and well-organized protocol prior to submission. The tool is intended to support protocol drafting and does not replace investigator review or responsibility for the accuracy and completeness of the submitted materials.
  • OSP

  • COI

    Coming soon...
  • General

    • What would the new eRA system be named?
      myUABResearch will be the name of the new system.
    • What system will replace IRAP?
      Huron Research Suite (HRS) has been selected as the replacement for IRAP.
    • What changes should I expect to see in the new eRA system?
      • Role based user dashboards which provide ease of use and transparency.
      • Enhanced reporting capabilities at the project, department, and school level.
      • Smart form technology which provides electronic submission to research offices.
      • Direct System-to-System (S2S) submission to grants.gov agencies such as NIH and CDC.
      • Automated system alerts informing researchers when important due dates are approaching.
    • Would the implementation have a big bang approach or phased approach?
      The current approach is to implement HRS in three phases:
      Phase 1:
      Grants (S2S), Agreements and Conflict of Interest
      Phase 2:
      IRB and Export Control
      Phase 3:
      IACUC and Vivarium Operations
    • Will the new system (myUABResearch) require more work for PIs?
      No. The new system will consolidate things like disclosures and external activities into one place. The new system will capture information via smartforms instead of submission of multiple PDFs and other required documents to an email inbox. Also, all approvals will be captured through electronic routing within the system.
    • Does the system allow for multiple project personnel to have edit and view access?
      Yes. Huron allows for proxy access for multiple roles.
    • What other prominent R1 institutions use HRS?
      Some HRS clients with academic medical centers are listed below...
      • Emory University
      • Icahn School of Medicine at Mount Sinai
      • New York University
      • Ohio State University
      • University of California
      • University of Florida
      • University of Minnesota
      • University of Pittsburgh
      • University of Texas Southwestern Medical Center
      • University of Washington
      • University of Wisconsin - Madison
      • Vanderbilt University
      Other notable HRS clients...
      • Auburn University
      • Boston University
      • Carnegie Mellon University
      • Case Western Reserve University
      • Children's Hospital of Philadelphia/li>
      • Florida State University
      • Johns Hopkins University
      • Lawrence Berkeley National Laboratory
      • Memorial Sloan Kettering Cancer Center
      • Michigan State University
      • National Aeronautics and Space Administration (NASA)
      • National Institutes of Health (NIH)
      • Northwestern University
      • Penn State University
      • Princeton University
      • RAND Corporation
      • Rockefeller University
      • Rutgers University
      • Sanford Health
      • Texas A&M University
      • University of Chicago
      • University of Cincinnati
      • University of Georgia
      • University of Houston
      • University of Kansas
      • University of Maryland, Baltimore School of Medicine
      • University of Miami
      • University of New Mexico
      • University of Southern California - CHLA
      • University of Tennessee
      • University of Texas - Austin
      • University of Texas Health Science Center San Antonio
      • University of Utah
      • University of Vermont
      • Wake Forest University
    • How can I be involved in testing?
      You should reach out to Amanda Capps, the eRA project manager, at This email address is being protected from spambots. You need JavaScript enabled to view it..
    • Who should we reach out to if we have any further questions?
      You should reach out to Amanda Capps, the eRA project manager, at This email address is being protected from spambots. You need JavaScript enabled to view it.. We also offer monthly myUABResearch Office Hours if you prefer to bring your questions there.

       

      myUABResearch Office Hours
      Second Wednesday Every Month
      11am-12pm
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