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Center for Exercise Medicine

Moving Research into Medicine

The UAB Center for Exercise Medicine (UCEM) focuses on improving the health and well-being of children and adults of all ages through acceleration of innovative, exercise-based interdisciplinary research across five pillars – precision, regeneration, rehabilitation, interaction, and sustainability.

Interested in participating in exercise research?

We are looking for volunteers for various exercise-based studies to help understand the role of exercise as medicine at the molecular, cellular and clinical levels. By participating, you receive supervised exercise training from certified trainers, valuable information about your health.

Opportunities to Participate

Research

The center's research mission is to build a foundation of excellence for innovative and large-scale, multi-investigator studies that help advance the field of exercise biology and medicine.

Our Studies and Services

Training & Education

UCEM offers a multi-tiered education and training program structured for exercise medicine researchers ranging from undergraduates to senior scientists.

Precision High-Intensity Training Through Epigenetics

This study is designed to assess whether changes to genes in the body is a primary way by which specific training causes those changes in the body and responses to exercise. PHITE is a 12-wk, two-arm, single-blind, randomized, exercise dose-response trial comparing two intensities of combined exercise training – Moderate Intensity vs. High-Intensity – to determine the effect of exercise dose on performance optimization and the underlying molecular mechanisms, with a focus on epigenetics.

The term epigenetics refers to heritable changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence; i.e. a change in phenotype (the set of observable characteristics of an individual resulting from the interaction of its genotype with the environment) without a change in genotype (the genetic constitution of an individual organism). This in turn affects how cells read the genes. Epigenetic change is a regular and natural occurrence but can also be influenced by several factors including age, the environment/lifestyle, and disease state.

Come join our PHITE Club!

Benefits: Participants will receive supervised exercise training from certified trainers at our state-of-the-art exercise clinical trials facility, valuable information about their health, and upto $1000 compensation for their time. 
Participants: Must be 18-27 years of age; no history of regular endurance or resistance training within the past year; must meet all other inclusion and exclusion criteria determined during screening.

  • "I have noticed many positive changes in myself since participating in PHITE. Initially, I was proud that I completed the study (it is quite a time commitment!) and I felt healthier, stronger, and more energetic. COVID-19 hit just as I finished the study. While I wasn't able to take everything I learned and put it into practice in the gym I did adapt what I learned in PHITE to home workouts.

    The personal training from exercise physiologists was one of the main reasons I wanted to participate in PHITE. As someone without a strength training background, I've always been intimidated by and generally avoided that area of the gym. Individual training empowered me to confidently and safely incorporate strength training into my workouts moving forward. Each exercise physiologist I worked with was incredible - kind, patient, and tough!"

    Elizabeth Blunck
    PHITE Completer

  • "Participating in PHITE really helped me improve my physical and mental health. It wasn’t easy waking up at 5 a.m. every other day, especially as a college student. But after just a few weeks of hard work and determination, it became a lot easier. Once I completed the study, I saw changes in my body that I haven’t seen before. And I began to naturally wake up at 5 a.m.

    I’ve tried personal workout plans in the past and always ended up quitting after a couple of weeks. Having an actual trainer to teach and push me till every last repetition really helped me continue the study. The physiologists were well informed on the basic exercises and were great motivators. This study gives participants an opportunity to change their lives through exercise and discipline. It won’t be easy at the beginning and you will feel the urge to quit. But if you keep going and never give up, you’ll feel a huge sense of accomplishment at the end. "

    Kenneth Paik
    PHITE Completer

  • "I definitely grew stronger over the course of 12 weeks and my body adapted really well to the specific training regimen that I was prescribed. The personal training was very beneficial. The knowledge and wisdom that the trainers possess is outstanding and they really helped me over some major hurdles during the training. Shout out to Brandon! I’m still using his helpful tip when doing a barbell squat.

    To a future participant, I would say the training, knowledge, and one-on-one attention you receive are well worth the time you spend doing the study. You’ll learn so much about your body and you’ll find out some pretty interesting data as it relates to your physical makeup."

    Martin Elston
    PHITE Completer

  • "I was stronger and more in shape than I had been in years. I felt like a freshman athlete again. The tips and advice I received from the exercise physiologists were phenomenal. It helped me then and it will help me in the future in preventing injury during workouts. I would recommend a future participant to stick with the program. It gets tough but you'll learn things you can use forever and come out of it stronger than you are."

    Ali El-husari
    PHITE Completer

Interested in participating and want to learn more?

Please complete the questionnaire below and a member of our research staff will contact you soon. You may also call 205-996-3569 or email phite@uab.edu. Thank you for your interest!

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